Month: June 2020

Jun 04 2020

Medicine, Biotech, Research

Reviewing Proteomic Studies of Cellular Senescence

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In today’s open access paper, the authors survey the work of the past decade in the use of proteomics to assess the consequences of cellular senescence. Senescent cells accumulate with...

Jun 04 2020

Daily News

The Role of Autophagy in the Beneficial Effects of Exercise

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Autophagy is the name given to a collection of processes responsible for recycling damaged or otherwise unwanted structures and proteins in the cell. With age, autophagy becomes less efficient. Many...

Jun 04 2020

Daily News

Targeting the Failure of Mitophagy as a Basis for Treating Age-Related Disease

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Evidence strongly suggests that the global faltering of mitochondrial function throughout the body with advancing age has a lot to do with a decline in the effectiveness of mitophagy. Mitochondria...

Jun 03 2020

Medicine, Biotech, Research

The Negligible Senescence of Sea Urchins

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Aging as we understand it is almost a universal phenomenon in animals. Clearly there is something advantageous in evolutionary terms in having disposable individuals carry the immortal germline forward in...

Jun 03 2020

Daily News

Exercise Training Increases Capillary Density in a Mouse Model of Heart Failure

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Exercise is known to improve outcomes in heart failure patients, but there is a limit as to the data that can be obtained on mechanisms of action from human patients....

Jun 03 2020

Daily News

Antibodies that Target Toxic Amyloid-β Oligomers

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One possible expansion of present immunotherapies for Alzheimer’s disease is to more specifically track and target oligomeric forms of amyloid-β. Efforts to reduce amyloid-β in the brain have, after many...

Jun 02 2020

Medicine, Biotech, Research

Towards a Better Understanding of Particulate Air Pollution and Dementia Risk

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There is evidence for particulate air pollution to raise the risk of age-related diseases via mechanisms such as increased levels of chronic inflammation. While the burden of age-related disease varies...

Jun 02 2020

Daily News

BCL-xL as a Longevity Gene

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BCL-xL is a mitochondrial protein that acts to suppress the programmed cell death response of apoptosis, and is overexpressed in some cancers, as well as in senescent cells. Thus small...

Jun 02 2020

Daily News

Longer Female Life Spans Vary Widely by Species and Likely Have Complex Roots

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In most species, including our own, females live longer than males. Why this is the case is likely one of those simple questions that lacks a simple answer. At the...

Jun 01 2020

Newsletters

Fight Aging! Newsletter, June 1st 2020

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....