Skincare

Oct 14 2026

Daily News

A History of Research into Cellular Senescence

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Cells become senescent in response to various forms of damage and stress, including the stress induced by reaching the Hayflick limit on replication. This was first described in the context...

Oct 14 2026

Medicine, Biotech, Research

Age-Related Decline in Chaperone-Mediated Autophagy Impairs Clearance of Senescence Cells

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Cells become senescent in response to stress and damage, in response to tissue injury, but most commonly upon reaching the Hayflick limit to replication. A senescent cell ceases to replicate,...

Oct 13 2026

Daily News

Functional Connectivity Changes in the Aging Brain are Different in Alzheimer’s Disease Patients

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Functional connectivity is a measure of neuronal activity over time in different parts of the brain, assessed using MRI to detect the increased blood flow that accompanies increased neuronal activity....

Oct 13 2026

Daily News

Transcriptomic Approaches to Guiding the Discovery of Geroprotective Compounds

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A great deal of drug discovery starts by screening compounds from the vast libraries of molecules that exist. The libraries are too large to screen everything (and even then the...

Oct 12 2026

Newsletters

Fight Aging! Newsletter, October 12th 2026

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

Oct 12 2026

Medicine, Biotech, Research

Arguing that Methionine Restriction is Actually Cysteine Restriction

by Consultant

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A reduced intake of calories triggers protective responses to low nutrient availability, dramatically altering the operation of cellular metabolism. For so long as adequate levels micronutrients are still ingested, this...

Oct 11 2026

Daily News

IGFBP5 Overexpression Reduces Dental Follicle Stem Cell Senescence in the Treatment of Periodontitis

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Dental follicle stem cells can be used as a basis for regenerative cell therapy in the treatment of periodontitis, the prevalent form of gum disease, and a condition that becomes...

Oct 11 2026

Daily News

Assessing the Burden of Somatic Mutation in Healthy Individuals versus Cancer Patients

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Cancers are primarily age-related conditions for a range of reasons, such as the decline of the immune system’s ability to find and destroy cancerous cells, a rising burden of senescent...

Oct 10 2026

Medicine, Biotech, Research

Succinate Dehydrogenase as a Regulator of the Regenerative Capacity of the Heart

by Consultant

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The tissues of the mammalian body span a broad range of regenerative capacity, from the highly regenerative liver to the minimal regenerative capabilities of the brain and the heart. We...

Oct 10 2026

Daily News

An Aging Clock Built on Speech Analysis Data

by Consultant

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Any sufficiently complex set of biological data that changes with age can be used as the basis for an aging clock. Well established machine learning techniques can identify patterns and...