Month: September 2020

Sep 03 2020

Medicine, Biotech, Research

A Bidirectional Relationship Between the Gut Microbiome and Aging

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The gut microbiome is influential on health over the long term, possible as much so as exercise. That said, research related to aging in this part of the field is...

Sep 03 2020

Daily News

Is Age-Related Polyploidy a Beneficial Adaptation to a Damaged Environment?

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Cells with abnormal chromosome counts, a state known as aneuploidy, are considered to be a problem. The evidence suggests that such cells accumulate with age, a form of damage and...

Sep 03 2020

Daily News

mTOR in the Cerebrovascular Dysfunction that Contributes to Neurodegenerative Disease

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Aging brings considerable disruption to the vascular system: stiffening of blood vessels; hypertension that damages delicate tissues; a loss of capillary density resulting in reduced delivery of nutrients and oxygen;...

Sep 02 2020

Medicine, Biotech, Research

An Update on Lygenesis: Functional Liver Organoids in the Lymph Nodes of Pigs

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Lygenesis is the company founded to conduct the clinical development of research into the use of lymph nodes to support the growth and function of organoids. Lymph nodes are found...

Sep 02 2020

Daily News

A Better Chondroitinase ABC to Break Down Nerve Tissue Scarring

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Researchers here report on their successful redesign of the chondroitinase ABC enzyme, capable of degrading a form of scarring that forms following nervous system injury. This scarring inhibits regrowth of...

Sep 02 2020

Daily News

Theophylline Produces Accelerated Remyelination in the Central Nervous System of Mice

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The myelin sheathing around axons is necessary for the proper function of nervous system tissue. Demyelinating conditions such as multiple sclerosis, an autoimmune disease in which the immune system attacks...

Sep 01 2020

Medicine, Biotech, Research

CCR2 Inhibition Promotes Muscle Regeneration in Aged Mice

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Chronic inflammation is an important component of aging. The immune system becomes overactive, provoked by a range of problems that include persistent viral infections, increased amounts of molecular debris from...

Sep 01 2020

Daily News

The RNAAgeCalc Transcriptional Aging Clock

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Omics data provides a wealth of metrics that correlate with age, quite well in some cases. Weighted combinations of CpG site methylation status, protein levels, and RNA transcript levels have...

Sep 01 2020

Daily News

Comparing the Genetics of Large and Small Long-Lived Rodents

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Research into the comparative biology of aging seeks to identify important mechanisms determining life span and the progression of aging by comparing different near neighbor species with very different life...