Month: October 2020

Oct 12 2020

Newsletters

Fight Aging! Newsletter, October 12th 2020

by Consultant

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

Oct 10 2020

Medicine, Biotech, Research

Fecal Microbiota Transplantation from Old Mice to Young Mice Impairs Cognitive Function

by Consultant

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The microbiome of the gut changes with age, and this is presently thought to have a meaningful influence over the course of aging. It is perhaps in the same ballpark...

Oct 10 2020

Daily News

Incorporating Microelectronics into Bioartificial Blood Vessels

by Consultant

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Researchers here report on an interesting proof of concept, incorporating electronic device capabilities into the flexible biomaterials used as scaffolding for blood vessel tissue engineering. As a next generation technology...

Oct 10 2020

Daily News

In Search of Common Transcriptional Regulators of Aging

by Consultant

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Are there common regulators of aging to be found among transcription factors? Sweeping, complex, tissue-specific and species-specific changes in gene expression take place over the course of aging. If these...

Oct 09 2020

Medicine, Biotech, Research

Lamenting the Incomplete Understanding of Human Immunosenescence

by Consultant

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The immune system is inconveniently complicated. Aging is also inconveniently complicated. The overlap between the two is a particularly dark forest for the research community, with few well-tracked paths. The...

Oct 09 2020

Daily News

Klotho in Aging and the Failing Kidney

by Consultant

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Klotho is one of the few longevity-associated genes with robustly demonstrated effects in both directions: reduce its expression and life span is reduced, increase its expression and life span is...

Oct 09 2020

Daily News

An Example of the Beneficial Role of Senescence in Injury

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Researchers here provide an interesting demonstration of the beneficial role of transient cellular senescence in injury. Applying senolytics to selectively destroy senescent cells immediately following traumatic injury greatly worsens the...

Oct 08 2020

Medicine, Biotech, Research

Delivery of T Cell Progenitor Cells as an Approach to Thymic Regeneration

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The thymus is a small organ in which thymocytes generated in the bone marrow mature to become T cells of the adaptive immune system. Unfortunately, the thymus atrophies with age,...

Oct 08 2020

Daily News

Markers of Chronic Inflammation Correlate with Age-Related Loss of Muscle Mass and Strength

by Consultant

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Chronic inflammation is a sizable component of aging. The immune system becomes inappropriately overactive, disrupting its normal participation in tissue maintenance, and producing alterations in the signaling environment that change...

Oct 08 2020

Daily News

Lef1 Enables Skin Regeneration Without Scarring in Mice

by Consultant

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To achieve regeneration without scarring is an important goal in the medical research community. Some species are capable of proficient regeneration of even whole limbs or internal organs, but mammalian...