Month: October 2020

Oct 07 2020

Medicine, Biotech, Research

Targeting Senescent Cells to Reverse the Aging of the Heart

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Almost a decade has passed since the first compelling demonstration that clearance of senescent cells in mice could produce rejuvenation. This validated decades of prior evidence, largely ignored in the...

Oct 07 2020

Daily News

Dopaminergenic Neurons Transplanted into Mouse Brains Integrate Into Neural Circuits and Improve Parkinson’s Symptoms

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Researchers here demonstrate that human dopaminergenic neurons, the class of cell lost in Parkinson’s disease, can integrate into neural circuits and improve motor function when transplanted into mice. The challenge...

Oct 07 2020

Daily News

The More Time Spent with High Blood Cholesterol, the Greater the Lifetime Risk of Heart Disease

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Researchers here suggest that the processes of atherosclerosis, leading to the buildup of fatty deposits that narrow and weaken blood vessels, are cumulative over time. One of the risk factors...

Oct 06 2020

Medicine, Biotech, Research

There is No Such Thing as Aging

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Today’s open access commentary is intended to provoke discussion on the topic of how aging is thought about and presented, particularly at the intersection between the scientific community and the...

Oct 06 2020

Daily News

Senolytics as an Arm of Regenerative Medicine for the Elderly

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Senolytic therapies are those that selectively destroy the senescent cells that accumulate in tissues with age. These cells secrete a potent mix of signals that produce chronic inflammation and degrade...

Oct 06 2020

Daily News

Making the Leap from Mice to Humans in the Treatment of Aging

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This commentary makes the point that the development of interventions to slow and reverse aging is moving along at some pace in mice, the field expanding year after year, but...

Oct 05 2020

Newsletters

Fight Aging! Newsletter, October 5th 2020

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

Oct 03 2020

Uncategorized

Planaria flatworms can be alternative screening tool to avoid rabbit skin testing

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A new, accurate screening tool for clinical skin products has been developed which uses flatworms rather than rabbits.

Oct 03 2020

Medicine, Biotech, Research

Building the Glucosepane Research Toolkit Continues with the Creation of Anti-Glucosepane Antibodies

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Glucosepane is likely the most important form of persistent cross-linking in aging human tissue. There is some remaining uncertainty, but it appears that the vast majority of cross-links in old...

Oct 03 2020

Daily News

Fructose Metabolism in Alzheimer’s Disease

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The degree to which Alzheimer’s disease is a lifestyle condition is an interesting question. A good deal of research points to insulin resistance in the brain as important in the...