Month: October 2020

Oct 03 2020

Daily News

Insight into How Loss of Functional TDP-43 Contributes to ALS and Frontotemporal Dementia

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TDP-43 is one of a number of proteins that can misfold in ways that cause neurodegeneration, either via aggregation into solid deposits, or via a diminished amount of functional protein...

Oct 02 2020

Medicine, Biotech, Research

On the Aging of the Germline and Rejuvenation in Embryos

by Consultant

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It is clearly the case that cells and tissues are in principle capable of rejuvenation. Individuals age, but their offspring are born young. The germline in adults is protected in...

Oct 02 2020

Daily News

Visceral Fat Tissue is the Major Determinant of Mortality Due to Excess Body Weight

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It is the metabolic activity of visceral fat packed around abdominal organs that determines most of the harmful consequences of being overweight, not the subcutaneous fat deposits elsewhere in the...

Oct 02 2020

Daily News

Ketone Body β-hydroxybutyrate Inhibits Inflammation to Reduce Alzheimer’s Pathology in a Mouse Model

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Ketosis is a response to low dietary intake of carbohydrates, and one of the mechanisms by which calorie restriction produces benefits to health and longevity. A ketogenic diet attempts to...

Oct 01 2020

Politics and Legislation

A Research Agenda for Aging in China

by Consultant

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Today’s review paper is a look at views on aging on the other side of the world, a counterpoint to commentaries from US and European sources. It is interesting to...

Oct 01 2020

Daily News

Cellular Senescence as a Mediator of Age-Related COVID-19 Severity

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Wherever we find the intersection of inflammation and aging, important in many age-related conditions, it has become the case that attention is drawn to the role of senescent cells. Senescent...

Oct 01 2020

Daily News

Learning is Damaged Before Memory in the Progression to Clinical Alzheimer’s

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Researchers searching for better ways to assess the early progression towards clinical Alzheimer’s disease have established what looks like a decent way to measure loss of learning capability, a decline...