Author: Consultant

Oct 05 2020

Newsletters

Fight Aging! Newsletter, October 5th 2020

by Consultant

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

Oct 03 2020

Uncategorized

Planaria flatworms can be alternative screening tool to avoid rabbit skin testing

by Consultant

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A new, accurate screening tool for clinical skin products has been developed which uses flatworms rather than rabbits.

Oct 03 2020

Daily News

Insight into How Loss of Functional TDP-43 Contributes to ALS and Frontotemporal Dementia

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TDP-43 is one of a number of proteins that can misfold in ways that cause neurodegeneration, either via aggregation into solid deposits, or via a diminished amount of functional protein...

Oct 03 2020

Medicine, Biotech, Research

Building the Glucosepane Research Toolkit Continues with the Creation of Anti-Glucosepane Antibodies

by Consultant

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Glucosepane is likely the most important form of persistent cross-linking in aging human tissue. There is some remaining uncertainty, but it appears that the vast majority of cross-links in old...

Oct 03 2020

Daily News

Fructose Metabolism in Alzheimer’s Disease

by Consultant

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The degree to which Alzheimer’s disease is a lifestyle condition is an interesting question. A good deal of research points to insulin resistance in the brain as important in the...

Oct 02 2020

Daily News

Visceral Fat Tissue is the Major Determinant of Mortality Due to Excess Body Weight

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It is the metabolic activity of visceral fat packed around abdominal organs that determines most of the harmful consequences of being overweight, not the subcutaneous fat deposits elsewhere in the...

Oct 02 2020

Daily News

Ketone Body β-hydroxybutyrate Inhibits Inflammation to Reduce Alzheimer’s Pathology in a Mouse Model

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Ketosis is a response to low dietary intake of carbohydrates, and one of the mechanisms by which calorie restriction produces benefits to health and longevity. A ketogenic diet attempts to...

Oct 02 2020

Medicine, Biotech, Research

On the Aging of the Germline and Rejuvenation in Embryos

by Consultant

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It is clearly the case that cells and tissues are in principle capable of rejuvenation. Individuals age, but their offspring are born young. The germline in adults is protected in...

Oct 01 2020

Politics and Legislation

A Research Agenda for Aging in China

by Consultant

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Today’s review paper is a look at views on aging on the other side of the world, a counterpoint to commentaries from US and European sources. It is interesting to...

Oct 01 2020

Daily News

Cellular Senescence as a Mediator of Age-Related COVID-19 Severity

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Wherever we find the intersection of inflammation and aging, important in many age-related conditions, it has become the case that attention is drawn to the role of senescent cells. Senescent...