Author: Consultant

Jul 18 2020

Daily News

Efforts Continue to Use COVID-19 as a Learning Moment Regarding the Costs of Aging

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Near everyone who dies from the SARS-Cov-2 virus responsible for the COVID-19 pandemic is old. The old are vulnerable firstly because their immune systems are much diminished in effectiveness, and...

Jul 17 2020

Medicine, Biotech, Research

Reviewing Present Thought on the Evolution of the Calorie Restriction Response

by Consultant

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The practice of calorie restriction involves reducing calorie intake by up to 40% while maintaining an optimal intake of micronutrients. It can meaningfully extend life span in short-lived species such...

Jul 17 2020

Daily News

Mifepristone Slows Aging in Flies

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Researchers here note that mifepristone, an abortifacient drug, slows aging in flies. This is interesting, but the mechanisms of action so far have the look of being quite specific to...

Jul 17 2020

Daily News

Targeting Senescent Cells in the Heart

by Consultant

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Senescent cells accumulate with age, and their inflammatory secretions disrupt tissue structure and function. In the heart, the presence of senescent cells contributes to fibrosis, hypertrophy, and other aspects of...

Jul 16 2020

Medicine, Biotech, Research

In Rats, Navitoclax Removes Senescent Chondrocytes that Contribute to Osteoarthritis

by Consultant

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Senescent cells are created constantly throughout life, largely as a result of somatic cells reaching the Hayflick limit on replication, but the pace at which they are cleared by programmed...

Jul 16 2020

Daily News

Sheer Stress in the Aging Heart Makes Immune Cells Inflammatory, Accelerating Cardiovascular Disease

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Researchers here note a process by which the hardening of heart valves, known as aortic valve stenosis, accelerates in its later stages. The condition causes greater sheer stress in blood...

Jul 16 2020

Daily News

On Defining What it Means to Be Old

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An increasing interest in intervening in the aging process, in treating aging as a medical condition, inevitably produces a greater interest in measuring aging. When is an individual old? Even...

Jul 15 2020

Medicine, Biotech, Research

Repetitive Element Activity is Reduced in Mice Subject to Interventions that Modestly Slow Aging

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Today’s open access paper is a companion piece to a recent discussion of repetitive element activity as a potential biomarker of biological aging. In today’s paper, the authors note that...

Jul 15 2020

Daily News

Thermoregulation is Impaired by Aging

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The old are more vulnerable to all stresses, and heat is no exception. Older people make up a majority of the fatalities in heatwaves. This topic isn’t frequently discussed in...

Jul 15 2020

Daily News

Lipocalin 2 as a Link Between Metabolic Syndrome and Neuroinflammation

by Consultant

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Obesity and its immediate consequences, such as non-alcoholic fatty liver disease and type 2 diabetes, are associated with greater neuroinflammation and risk of dementia. Excess visceral fat tissue does its...