Author: Consultant

Jun 19 2020

Medicine, Biotech, Research

Fitting Senescent Cells into a Modified Amyloid Cascade Hypothesis of Alzheimer’s Disease

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The amyloid cascade hypothesis is the earliest coherent view of the development of Alzheimer’s disease. In this view, the condition begins with the slow aggregation of amyloid-β over many years,...

Jun 19 2020

Daily News

Stiffening of the Extracellular Matrix Contributes to Age-Related Muscle Impairment

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In this interesting open access paper, the authors explore the contribution of changes in the extracellular matrix to the deterioration of muscle function that takes place with aging. The extracellular...

Jun 19 2020

Daily News

Repetitive Elements as a Transcriptomic Biomarker of Aging

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Retrotransposons are receiving more attention in the context of aging these days. They are the remnants of ancient viruses, capable of copying themselves around the genome. The mechanisms repressing this...

Jun 18 2020

Exercise, Featured, Fitness, Programs

Training zones – getting the BEST ROI on your exercise

by Consultant

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If you are anything like me, you hate wasting time and are looking for the best return on investment (ROI) on your exercise efforts. As a result, to drive my...

Jun 18 2020

Medicine, Biotech, Research

An Example to Illustrate Why Navitoclax is Not a Suitable Clinical Senolytic Drug

by Consultant

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Senolytic therapies are those that selectively destroy senescent cells. Cells that become senescent grow in size, cease to replicate, and generate a potent mix of molecules known as the senescence-associated...

Jun 18 2020

Daily News

Blood Pressure Control Increases Life Expectancy Even in the Most Frail Elderly People

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Chronically raised blood pressure, or hypertension, is highly damaging to tissues throughout the body. It is an important mechanism linking the molecular damage of aging to gross structural damage to...

Jun 18 2020

Daily News

Retraining the Immune System to Turn Off Autoimmunity

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This interesting study suggests that it may be possible to turn off many forms of autoimmunity by inducing tolerance, in a comparatively simple manner, to the specific fragment of a...

Jun 17 2020

Uncategorized

Wearable patch may provide new treatment option for skin cancer

by Consultant

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Innovators have created a novel wearable patch to provide an improved treatment experience for people with melanoma. The researchers developed a novel wearable patch with fully miniaturized needles, enabling unobtrusive...

Jun 17 2020

Medicine, Biotech, Research

Molecular Changes in the Lens of the Eye as a Potential Biomarker of Biological Age

by Consultant

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The search for viable biomarkers of aging is an active field of research. The ability to rapidly and cheaply assess biological age, the burden of cell and tissue damage and...

Jun 17 2020

Daily News

Threonine Restriction Promotes Health in Mice

by Consultant

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Calorie restriction, eating up to 40% fewer calories while maintaining optimal micronutrient intake, improves health and reliably extends life in most species. In humans it produces robust improvements in health,...