Author: Consultant

May 28 2020

Daily News

Delivery of Cadherin-13 Slows the Onset of Osteoporosis in Mice

by Consultant

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Bone is a dynamic structure, constantly built up by osteoblasts and torn down by osteoclasts. In youth there is a balance between these two cell types, but the processes of...

May 28 2020

Medicine, Biotech, Research

Calorie Restriction versus the Aging of Microglia

by Consultant

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Microglia are immune cells of the brain, analogous to macrophages in the rest of the body. They take on a broad range of tasks: chasing down pathogens; clearing up cell...

May 28 2020

Daily News

Somatic Chromosomal Mosaicism as a Mechanism of Aging and Disease

by Consultant

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Stochastic mutational damage to nuclear DNA occurs constantly in the body, and near all of it is quickly repaired. Most unrepaired damage occurs in DNA that isn’t used, or the...

May 27 2020

2020, Anti-Aging, Body Treatments, CoolSculpting, Necks

The Latest on Neck Tightening (#2/2)

by Consultant

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This is the second of two.  Neck tightening has been the ‘holy grail’ of nonsurgical for quite some time, with good options for prevention of sagging by starting early, as...

May 27 2020

Medicine, Biotech, Research

Vaccination as a Limited Option for Removal of Senescent Cells

by Consultant

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In today’s open access paper, the authors demonstrate a form of vaccination against a surface marker that appears on a subset of senescent T cells that reside in fat tissue,...

May 27 2020

Daily News

Age-Impaired Autophagy Makes CD4+ T Cells Inflammatory

by Consultant

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Here, researchers discuss data that sheds light on the way in which age-related declines in autophagy, related mitochondrial dysfunction due to impairment of mitochondrial autophagy, and decline of the immune...

May 27 2020

Daily News

An Analysis of the Gray Whale Transcriptome in the Context of Longevity

by Consultant

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Much of the comparative biology of aging involves study of long-lived mammals in an attempt to understand which mechanisms determine species longevity. It is possible that a better understanding of...

May 26 2020

Medicine, Biotech, Research

Secreted Stem Cell Factors as a Treatment for Male-Pattern Baldness

by Consultant

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Both hair graying and hair loss with age are well researched topics, but there remains considerable uncertainty over which of the possible mechanisms involved are the most relevant, or most...

May 26 2020

Daily News

Is Ageism a Useful Explanation for Lack of Progress Towards Rejuvenation Therapies?

by Consultant

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While ageism certainly exists, I’ve never really liked the use of ageism as an explanation for the lack of progress towards rejuvenation therapies, and this in an era of biotechnology...

May 26 2020

Daily News

HDAC1 Activators Improve DNA Repair in Neurons to Treat Cognitive Decline

by Consultant

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HDAC1 is involved in a form of DNA repair, but levels decline with age, as well as in Alzheimer’s disease. This leads to a greater accumulation of unrepaired oxidative DNA...