Category: Daily News

Jul 03 2020

Daily News

PTB Inhibition Converts Astrocytes into Neurons, Reverses Symptoms in a Mouse Model of Parkinson’s Disease

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Researchers here expand upon a fortuitous discovery that inhibition of the gene PTB causes a number of cell types to change into neurons, using this finding as the basis for...

Jul 03 2020

Daily News

Obesity Correlates with Higher Dementia Risk

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Excess visceral fat tissue generates chronic inflammation via a range of mechanisms, including an accelerated creation of senescent cells. Most of the commmon age-related conditions have an inflammatory component, and...

Jul 02 2020

Daily News

Overexpression of Mitochondrial Peptide Humanin as a Potential Approach to Slowing Aging

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Researchers have discovered a number of mitochondrial peptides that influence cell and tissue health. Here, it is demonstrated that upregulation of humanin is sufficient to extend life in nematode worms....

Jul 02 2020

Daily News

Targeting Cellular Senescence as an Intervention in Aging

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Senolytic drugs that destroy senescent cells, and later on, other senotherapies that either prevent senescence or block the senescence-associated secretory phenotype (SASP), are going to be very important in the...

Jul 01 2020

Daily News

More on the Anti-Inflammatory Activities of BPIFB4 in Long Lived Individuals

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A research team has recently investigated a role for BPIFB4 in human longevity. They have identified a variant of this gene that appears more often in a population of long-lived...

Jul 01 2020

Daily News

An Analysis of the Grey Whale Transcriptome

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Whales are among the longest lived mammals, and thus of interest to researchers investigating the comparative biology of aging. There is the hope that examining the biochemistry of mammals with...

Jun 30 2020

Daily News

Cross-Links as the Missing Hallmark of Aging

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Researchers here argue that it was a mistake to omit from the hallmarks of aging of cross-links and other forms of persistent modification to extracellular matrix molecules. Cross-links degrade the...

Jun 30 2020

Daily News

Considering Mitochondrial Quality Control in Greater Detail

by Consultant

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Loss of mitochondrial function is important in aging. Mitochondria are the power plants of the cell, a herd of bacteria-like organelles that contain their own mitochondrial DNA, constantly replicate by...

Jun 27 2020

Daily News

Germline Mutation Rate as an Insight into the Pace of Aging

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DNA sequencing over generations can be used to determine individual rates of germline mutation, as mutations present in the child but not the parent must have occurred in the parent...

Jun 27 2020

Daily News

T Cells Must Work Harder to Survive in an Old Body

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T cells of the adaptive immune system collectively become less functional with age. The immune system as a whole becomes more inflammatory and less effectively, a state described by the...