Category: Daily News

Jun 26 2020

Daily News

Demonstrating a Senolytic Chimeric Antigen Receptor T Cell Therapy

by Consultant

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Chimeric antigen receptor (CAR) T cell therapies target specific surface features on other cells by providing T cells with a way to recognize that feature – the CAR. T cells...

Jun 26 2020

Daily News

Sedentary Behavior Raises the Risk of Cancer Mortality

by Consultant

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Living a sedentary lifestyle is known to be harmful to long term health, raising the risk of age-related disease and mortality. Researchers here show that a sedentary life specifically increases...

Jun 25 2020

Daily News

Lower Socioeconomic Status Correlates with Faster Age-Related Decline

by Consultant

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There is a well-established web of correlations between life expectancy, wealth, intelligence, education, and social status. It is challenging to pick apart the underlying mechanisms, however, given demographic and epidemiological...

Jun 25 2020

Daily News

Using the Metabolome to Produce an Aging Clock

by Consultant

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It has been a while now since the development of the first epigenetic clock, a weighted combination of DNA methylation sites that correlates tightly with chronological age. More interesting is...

Jun 24 2020

Daily News

The Immune Response to Tumors Changes with Age

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The interaction between the immune system and tumor is meaningfully different in young and old individuals. The aging of the immune system makes near everything worse in health and physiology....

Jun 24 2020

Daily News

The Challenge of Cellular Senescence in Mesenchymal Stem Cell Therapy

by Consultant

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The accumulation of senescent cells in tissues throughout the body is a cause of aging, but it is also a phenomenon that occurs in cell cultures. Senescent cells do not...

Jun 23 2020

Daily News

Towards the Use of Epigenetic Clocks in Clinical Trials

by Consultant

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Despite the challenges inherent in the practical use of epigenetic clocks based on age-related changes in DNA methylation, clinical trials are forging ahead in the employment of these clocks. The...

Jun 23 2020

Daily News

A Central Role for p53 in Osteoporosis?

by Consultant

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Osteoporosis is the name given to the advanced stages of the characteristic age-related loss of bone strength and density. Bone tissue is constantly remodeled, created by osteoblasts and broken down...

Jun 20 2020

Daily News

Regular Physical Activity Reverses Frailty in the Old

by Consultant

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There is considerable evidence for the proposition that older people engage in too little physical activity. Our modern societies of comfort and our engines of transport enable a sedentary lifestyle,...

Jun 20 2020

Daily News

CD9 Expression in Cellular Senescence and Atherosclerosis

by Consultant

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Cellular senescence is important in the progression of aging, and targeted elimination of senescent cells has been shown to reverse the course of many age-related conditions in animal studies. Atherosclerosis...