Category: Medicine, Biotech, Research

Sep 11 2020

Medicine, Biotech, Research

Targeting Cellular Senescence to Heal Non-Healing Wounds

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An accumulation of senescent cells takes place throughout the body with age. Cells become senescent constantly, the vast majority as a consequence of hitting the Hayflick limit on replication of...

Sep 10 2020

Medicine, Biotech, Research

Connecting the Immune Response to Amyloid-β Aggregation in Alzheimer’s Disease via IFITM3

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It is well established that chronic inflammation in brain tissue contributes to the onset and progression of neurodegenerative conditions such as Alzheimer’s disease. Short-term inflammation is a necessary part of...

Sep 05 2020

Medicine, Biotech, Research

Assessing the Utility of Six of the Better Known Epigenetic Clocks in a Large Study Population

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Epigenetic clocks to measure age emerged from the ability to cost-effectively obtain the moment to moment epigenome of an individual, the distribution of epigenetic marks on nuclear DNA that control...

Sep 04 2020

Medicine, Biotech, Research

Stress Granules as a Therapeutic Target

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Stress granules are a comparatively poorly understood portion of the processes that a cell uses to maintain its protein machinery and component structures. When cells are subject to mild stress...

Sep 03 2020

Medicine, Biotech, Research

A Bidirectional Relationship Between the Gut Microbiome and Aging

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The gut microbiome is influential on health over the long term, possible as much so as exercise. That said, research related to aging in this part of the field is...

Sep 02 2020

Medicine, Biotech, Research

An Update on Lygenesis: Functional Liver Organoids in the Lymph Nodes of Pigs

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Lygenesis is the company founded to conduct the clinical development of research into the use of lymph nodes to support the growth and function of organoids. Lymph nodes are found...

Sep 01 2020

Medicine, Biotech, Research

CCR2 Inhibition Promotes Muscle Regeneration in Aged Mice

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Chronic inflammation is an important component of aging. The immune system becomes overactive, provoked by a range of problems that include persistent viral infections, increased amounts of molecular debris from...

Aug 29 2020

Medicine, Biotech, Research

Investigating the Cause of Irregular Heartbeat Following Cell Therapy for Regeneration of Heart Tissue

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The promise of cell therapies is twofold. Firstly, the ability to regenerate from injuries that do not normally heal, such as severed nerves, or large loss of tissue mass. Secondly,...

Aug 28 2020

Medicine, Biotech, Research

Aging as a Target is a New Therapeutic Frontier

by Consultant

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My attention was recently drawn to an open access commentary on the present early stage of the scientific initiative to treat aging as a medical condition. It was published earlier...

Aug 27 2020

Medicine, Biotech, Research

Age-Related Downregulation of Rubicon Causes Excessive Autophagy in Adipocytes, Contributing to Metabolic Dysfunction

by Consultant

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Autophagy is a vital collection of cellular maintenance processes in which proteins and structures are broken down and recycled for their component parts. In short-lived laboratory species, dysfunctional autophagy shortens...