Skincare

Sep 16 2020

Medicine, Biotech, Research

Alpha-Ketoglutarate Supplementation Modestly Increases Life Span in Mice

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Alpha-ketoglutarate supplementation has been shown to modestly extend life span and improve measures of health in old mice; the publicity materials here accompany the formal release of that paper. Recently,...

Sep 16 2020

Daily News

Using Direct Conversion of Cells to Investigate the Behavior of Aging Tissues

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The process of reprogramming used to produce induced pluripotent stem cells erases many of the marks of aging in cells taken from old tissues, such as epigenetic changes and declining...

Sep 16 2020

Daily News

Upregulation of Unacetylated Ghrelin Slows Age-Related Muscle Loss in Mice

by Consultant

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Ghrelin is best known for its role in the mechanisms of hunger, but it has two different forms, only one of which induces hunger. Both forms are known to affect...

Sep 15 2020

Uncategorized

DNA damage caused by migrating light energy

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Ultraviolet light endangers the integrity of human genetic information and may cause skin cancer. For the first time, researchers have demonstrated that DNA damage may also occur far away from...

Sep 15 2020

Medicine, Biotech, Research

Clearance of Senescent Cells Reverses the Peripheral Neuropathy Caused by Chemotherapy

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A primary goal of chemotherapy is to force cancerous cells into programmed cell death or cellular senescence. Cellular senescence is a state of growth arrest that should normally be triggered...

Sep 15 2020

Daily News

Increased Insulin Receptor Expression Improves Memory in Old Rats

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This is a interesting example of modulating the metabolism of the aging brain in order to improve its function, without any attempt to address the underlying cell and tissue damage...

Sep 15 2020

Daily News

Evidence for Familial Longevity to be Largely Cultural Rather than Genetic

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It is certainly possible that a small number of people have mutations or genetic variants that confer notable longevity. The small lineage exhibiting a PAI-1 loss of function mutation springs...

Sep 14 2020

Newsletters

Fight Aging! Newsletter, September 14th 2020

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

Sep 12 2020

Medicine, Biotech, Research

Hormone Therapy in Postmenopausal Women Correlates with Lesser Senescent Cell Signaling

by Consultant

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Beyond their use for conditions of severe hormone deficiency, hormone therapies are one of the higher profile approaches taken by the less rigorous, more dubious end of the “anti-aging” medical...

Sep 12 2020

Daily News

Dysfunction of the Blood-Brain Barrier as an Early Stage in the Progression to Dementia

by Consultant

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The blood-brain barrier is a lining of specialized cells that surrounds blood vessels passing through the brain. The barrier permits only certain molecules and cells to pass, isolating the tissue...