Skincare

Jul 21 2020

Medicine, Biotech, Research

Epigenetic Clocks are Quirky: the Biological Age of the Heart is Consistently Younger than Chronological Age

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Measures of biological age based on epigenetic marks, protein levels, transcriptomic profiles, and similar collections of biological data are proliferating rapidly. The first epigenetic clock, a weighted combination of DNA...

Jul 21 2020

Daily News

Type V Collagen Regulates the Degree of Scarring Following Heart Attack

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The heart regenerates poorly in mammals; functional tissue is replaced by scar tissue following injury, such as a the damaged caused in a heart attack. Researchers have recently found that...

Jul 21 2020

Daily News

Extracellular Matrix Remodeling Following Injury is Impaired in Aged Muscle

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The maintenance of muscle tissue declines with age, leading to both loss of muscle mass and strength, as well as impaired regeneration following injury. One of the more important aspects...

Jul 20 2020

Newsletters

Fight Aging! Newsletter, July 20th 2020

by Consultant

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

Jul 18 2020

Medicine, Biotech, Research

Gain and Loss of Flight as a Tool to Search for Import Factors in Longevity

by Consultant

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The capacity for flight is frequently associated with greater species longevity, such as in bats, for example. The present consensus suggests that the cellular adaptations needed to support the greater...

Jul 18 2020

Daily News

An Overactive Immune System Protects Against Infection at the Cost of More Rapid Aging

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Greater immune activity implies greater inflammation, which has a negative impact on tissue function if maintained over time. In aging, a great deal of damage is done by the chronic...

Jul 18 2020

Daily News

Efforts Continue to Use COVID-19 as a Learning Moment Regarding the Costs of Aging

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Near everyone who dies from the SARS-Cov-2 virus responsible for the COVID-19 pandemic is old. The old are vulnerable firstly because their immune systems are much diminished in effectiveness, and...

Jul 17 2020

Medicine, Biotech, Research

Reviewing Present Thought on the Evolution of the Calorie Restriction Response

by Consultant

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The practice of calorie restriction involves reducing calorie intake by up to 40% while maintaining an optimal intake of micronutrients. It can meaningfully extend life span in short-lived species such...

Jul 17 2020

Daily News

Mifepristone Slows Aging in Flies

by Consultant

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Researchers here note that mifepristone, an abortifacient drug, slows aging in flies. This is interesting, but the mechanisms of action so far have the look of being quite specific to...

Jul 17 2020

Daily News

Targeting Senescent Cells in the Heart

by Consultant

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Senescent cells accumulate with age, and their inflammatory secretions disrupt tissue structure and function. In the heart, the presence of senescent cells contributes to fibrosis, hypertrophy, and other aspects of...