Month: June 2020

Jun 23 2020

Daily News

Towards the Use of Epigenetic Clocks in Clinical Trials

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Despite the challenges inherent in the practical use of epigenetic clocks based on age-related changes in DNA methylation, clinical trials are forging ahead in the employment of these clocks. The...

Jun 22 2020

Newsletters

Fight Aging! Newsletter, June 22nd 2020

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

Jun 20 2020

2020, Anti-Aging, Asian Skin, Brown Spots

Really stubborn brown spots.

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Here are a few things to remember about brown spots. The longer they’ve been there the deeper their “roots” are, and the harder it will be to lighten them.  So...

Jun 20 2020

Medicine, Biotech, Research

Senescent Cardiomyocytes in Cardiovascular Disease

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Senescent cells accumulate in tissues throughout the body with age. Cells constantly become senescent as a result of wound healing, cancer suppression, the Hayflick limit on cellular replication, or damage...

Jun 20 2020

Daily News

CD9 Expression in Cellular Senescence and Atherosclerosis

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Cellular senescence is important in the progression of aging, and targeted elimination of senescent cells has been shown to reverse the course of many age-related conditions in animal studies. Atherosclerosis...

Jun 20 2020

Daily News

Regular Physical Activity Reverses Frailty in the Old

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There is considerable evidence for the proposition that older people engage in too little physical activity. Our modern societies of comfort and our engines of transport enable a sedentary lifestyle,...

Jun 19 2020

Medicine, Biotech, Research

Fitting Senescent Cells into a Modified Amyloid Cascade Hypothesis of Alzheimer’s Disease

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The amyloid cascade hypothesis is the earliest coherent view of the development of Alzheimer’s disease. In this view, the condition begins with the slow aggregation of amyloid-β over many years,...

Jun 19 2020

Daily News

Stiffening of the Extracellular Matrix Contributes to Age-Related Muscle Impairment

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In this interesting open access paper, the authors explore the contribution of changes in the extracellular matrix to the deterioration of muscle function that takes place with aging. The extracellular...

Jun 19 2020

Daily News

Repetitive Elements as a Transcriptomic Biomarker of Aging

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Retrotransposons are receiving more attention in the context of aging these days. They are the remnants of ancient viruses, capable of copying themselves around the genome. The mechanisms repressing this...

Jun 18 2020

Exercise, Featured, Fitness, Programs

Training zones – getting the BEST ROI on your exercise

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If you are anything like me, you hate wasting time and are looking for the best return on investment (ROI) on your exercise efforts. As a result, to drive my...