Month: September 2020

Sep 18 2020

Daily News

Metformin Found to Reduce Liver Inflammation

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Metformin produces a modest and unreliable extension of life in animal models, and human data shows a small increase in life span in diabetic patients. This is thought to work...

Sep 18 2020

Daily News

Lowered Body Temperature is Important in the Beneficial Calorie Restriction Response

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Calorie restriction lowers body temperature in mammals, but most research on how reduced calorie intake produces benefits to long-term health and longevity has focused on nutrient sensing as the primary...

Sep 17 2020

Uncategorized

Better material for wearable biosensors

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Researchers have used electrospinning to make porous silicone that allows sweat to evaporate.

Sep 17 2020

Healthy Life Extension Community

SENS Research Foundation Issues 2020 Annual Report

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The SENS Research Foundation, like the Methuselah Foundation it emerged from, is one of the more important organizations involved in the creation and shaping of the present R&D communities focused...

Sep 17 2020

Daily News

The Aging of Macrophages Impairs Peripheral Nerve Regeneration

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Macrophages of the innate immune system, cells derived from monocytes, are involved in many processes in tissue beyond merely hunting down invading pathogens. They are also important to the processes...

Sep 17 2020

Daily News

Targeting Inflammatory Microglia in the Treatment of Neurodegenerative Disease

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The immune cells of the central nervous system are distinct from those of the rest of the body. Innate immune cells such as microglia become increasingly inflammatory with advancing age,...

Sep 16 2020

Uncategorized

A new approach to understanding the biology of wound healing

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Researchers use discarded wound dressings as a novel and non-invasive way to study the mechanisms that promote healing.

Sep 16 2020

Medicine, Biotech, Research

Alpha-Ketoglutarate Supplementation Modestly Increases Life Span in Mice

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Alpha-ketoglutarate supplementation has been shown to modestly extend life span and improve measures of health in old mice; the publicity materials here accompany the formal release of that paper. Recently,...

Sep 16 2020

Daily News

Using Direct Conversion of Cells to Investigate the Behavior of Aging Tissues

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The process of reprogramming used to produce induced pluripotent stem cells erases many of the marks of aging in cells taken from old tissues, such as epigenetic changes and declining...

Sep 16 2020

Daily News

Upregulation of Unacetylated Ghrelin Slows Age-Related Muscle Loss in Mice

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Ghrelin is best known for its role in the mechanisms of hunger, but it has two different forms, only one of which induces hunger. Both forms are known to affect...