Month: October 2026

Oct 06 2026

Daily News

K21 Improves Mitochondrial Function in Macrophages, Extending Life in Nematode Worms

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The antimicrobial drug K21 acts via disruption of bacterial membranes, but is also known to produce improved wound healing, which suggests the involvement of mechanisms other than antimicrobial activity. Here,...

Oct 05 2026

Newsletters

Fight Aging! Newsletter, October 5th 2026

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

Oct 05 2026

Medicine, Biotech, Research

Accelerated Epigenetic Aging Correlates with Later Loss of Memory Function

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Aging clocks have yet to fulfill their promise, which is to produce a robust measure of biological aging that can be used to rapidly assess the results of potential therapies...

Oct 04 2026

Daily News

Where Next For Present Stem Cell Therapies?

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First generation stem cell therapies have become widespread; they are readily accessed in medical tourism clinics, and are also available for a range of issues in more regulated parts of...

Oct 04 2026

Daily News

Polyamines from the Gut Microbiome Affect Life Span in Flies

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The commensal microbes of the gut microbiome generate a range of metabolites that are beneficial or necessary to cell function. Levels of a number of these metabolites have been shown...

Oct 03 2026

Of Interest

Healthspan May Not Be a Usefully Robust Metric for Progress in Rejuvenation Biotechnology

by Consultant

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The effects of calorie restriction and even larger effects of growth hormone receptor knockout on the lifespan of mice have proven to be hard to beat. In large part, this...

Oct 03 2026

Daily News

APOEε2 Pericytes Provide a More Resilient Blood-Brain Barrier

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Why is the APOEε2 variant of the APOE gene associated with a lower risk of Alzheimer’s disease and slightly longer life expectancy? Past research has investigated the role of APOE...

Oct 02 2026

Medicine, Biotech, Research

A Conservative View of the Geroscience Endeavor

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An archly conservative viewpoint links establishment academia (“this thing you are doing has not yet been proven beyond all doubt to work”) to the thought leadership of Big Pharma (“this...

Oct 02 2026

Daily News

Possible Approaches to Engineering Better Therapeutic Delivery of Mitochondria

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Mitochondrial transplantation as a form of therapy to improve mitochondrial function in aged tissues has barely started as a going concern, and only a few patients have been treated in...

Oct 01 2026

Medicine, Biotech, Research

Don’t View mTOR as a Single Pharmaceutical Target, as Context Matters

by Consultant

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Of the many varied approaches to mimic some of the beneficial metabolic response to calorie restriction, mTOR inhibition is arguably the most well studied. Countless animal studies have been conducted,...