Author: Consultant

Sep 17 2020

Daily News

The Aging of Macrophages Impairs Peripheral Nerve Regeneration

by Consultant

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Macrophages of the innate immune system, cells derived from monocytes, are involved in many processes in tissue beyond merely hunting down invading pathogens. They are also important to the processes...

Sep 17 2020

Daily News

Targeting Inflammatory Microglia in the Treatment of Neurodegenerative Disease

by Consultant

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The immune cells of the central nervous system are distinct from those of the rest of the body. Innate immune cells such as microglia become increasingly inflammatory with advancing age,...

Sep 16 2020

Daily News

Using Direct Conversion of Cells to Investigate the Behavior of Aging Tissues

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The process of reprogramming used to produce induced pluripotent stem cells erases many of the marks of aging in cells taken from old tissues, such as epigenetic changes and declining...

Sep 16 2020

Medicine, Biotech, Research

Alpha-Ketoglutarate Supplementation Modestly Increases Life Span in Mice

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Alpha-ketoglutarate supplementation has been shown to modestly extend life span and improve measures of health in old mice; the publicity materials here accompany the formal release of that paper. Recently,...

Sep 16 2020

Uncategorized

A new approach to understanding the biology of wound healing

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Researchers use discarded wound dressings as a novel and non-invasive way to study the mechanisms that promote healing.

Sep 16 2020

Daily News

Upregulation of Unacetylated Ghrelin Slows Age-Related Muscle Loss in Mice

by Consultant

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Ghrelin is best known for its role in the mechanisms of hunger, but it has two different forms, only one of which induces hunger. Both forms are known to affect...

Sep 15 2020

Uncategorized

DNA damage caused by migrating light energy

by Consultant

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Ultraviolet light endangers the integrity of human genetic information and may cause skin cancer. For the first time, researchers have demonstrated that DNA damage may also occur far away from...

Sep 15 2020

Medicine, Biotech, Research

Clearance of Senescent Cells Reverses the Peripheral Neuropathy Caused by Chemotherapy

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A primary goal of chemotherapy is to force cancerous cells into programmed cell death or cellular senescence. Cellular senescence is a state of growth arrest that should normally be triggered...

Sep 15 2020

Daily News

Increased Insulin Receptor Expression Improves Memory in Old Rats

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This is a interesting example of modulating the metabolism of the aging brain in order to improve its function, without any attempt to address the underlying cell and tissue damage...

Sep 15 2020

Daily News

Evidence for Familial Longevity to be Largely Cultural Rather than Genetic

by Consultant

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It is certainly possible that a small number of people have mutations or genetic variants that confer notable longevity. The small lineage exhibiting a PAI-1 loss of function mutation springs...