Author: Consultant

Jun 03 2020

Daily News

Exercise Training Increases Capillary Density in a Mouse Model of Heart Failure

by Consultant

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Exercise is known to improve outcomes in heart failure patients, but there is a limit as to the data that can be obtained on mechanisms of action from human patients....

Jun 03 2020

Daily News

Antibodies that Target Toxic Amyloid-β Oligomers

by Consultant

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One possible expansion of present immunotherapies for Alzheimer’s disease is to more specifically track and target oligomeric forms of amyloid-β. Efforts to reduce amyloid-β in the brain have, after many...

Jun 02 2020

Daily News

Longer Female Life Spans Vary Widely by Species and Likely Have Complex Roots

by Consultant

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In most species, including our own, females live longer than males. Why this is the case is likely one of those simple questions that lacks a simple answer. At the...

Jun 02 2020

Daily News

BCL-xL as a Longevity Gene

by Consultant

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BCL-xL is a mitochondrial protein that acts to suppress the programmed cell death response of apoptosis, and is overexpressed in some cancers, as well as in senescent cells. Thus small...

Jun 02 2020

Medicine, Biotech, Research

Towards a Better Understanding of Particulate Air Pollution and Dementia Risk

by Consultant

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There is evidence for particulate air pollution to raise the risk of age-related diseases via mechanisms such as increased levels of chronic inflammation. While the burden of age-related disease varies...

Jun 01 2020

Newsletters

Fight Aging! Newsletter, June 1st 2020

by Consultant

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

May 30 2020

Uncategorized

Researchers identify mechanisms that make skin a protective barrier

by Consultant

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A research team has identified one of the mechanisms that establish the skin as a protective barrier, a breakthrough that is critical to understanding and treating common skin conditions including...

May 30 2020

Medicine, Biotech, Research

Disruption of T Cell Mitochondrial Function Produces Accelerated Aging Symptoms in Mice

by Consultant

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One has to be cautious about studies in which metabolism is broken in some way, and symptoms of aging start to appear earlier as a result. Whether or not this...

May 30 2020

Daily News

Reviewing the Prospects for Nicotinamide Mononucleotide Supplementation to Raise NAD+ Levels and Improve Health

by Consultant

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A fair amount of effort is presently put towards the exploration of supplements derived from vitamin B3 compounds (nicotinamide, niacin, nicotinamide riboside) that act as precursors to enable the manufacture...

May 30 2020

Daily News

Visceral Fat Behaves Differently in Long-Lived Dwarf Mice

by Consultant

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A few varieties of dwarf mice exhibit considerable longevity. They are produced via forms of mutation that disable portions of growth hormone metabolism, such as via growth hormone receptor knockout....