Category: Daily News

Aug 14 2020

Daily News

Exercise May Aid in Resisting Frailty and Cognitive Decline in Part via Effects on the Gut Microbiome

by Consultant

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The gut microbiome is influential on long-term health, and its quality declines with age. Microbial populations that produce beneficial metabolites such as butyrate or propionate decline in number, replaced by...

Aug 14 2020

Daily News

Should Rapamycin be Prescribed Ubiquitously as an Anti-Aging Supplement?

by Consultant

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Should rapamycin be prescribed ubiquitously as an anti-aging supplement? That is the question the authors of this commentary ask after a short overview of what is known of the beneficial...

Aug 13 2020

Daily News

A Fisetin Variant, CMS121, Slows Disease Progress in an Alzheimer’s Mouse Model

by Consultant

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The research materials here are of interest because fisetin has been shown to be a senolytic compound in mice, capable of selectively destroying harmful senescent cells. Other senolytics have reversed...

Aug 13 2020

Daily News

Considering the Use of Lasers to Break Down Harmful Protein Aggregates

by Consultant

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It is possible to tailor the frequency of laser light to selectively disrupt the bonds or structure of particular arrangements of molecules – such as, say, the harmful protein aggregates...

Aug 12 2020

Daily News

The Gut Microbiome Changes Shortly Before Death in Centenarians

by Consultant

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Extremely old people have such high mortality rates that studies such as this one here become practical, answering the question of how the gut microbiome changes in the final decline...

Aug 12 2020

Daily News

Overexpression of VRK-1 Extends Life Span in Nematode Worms

by Consultant

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A great many approaches exist to slow aging in short-lived laboratory species such as nematodes, flies, and mice. The example here is an illustrative example, similar to dozens of other...

Aug 11 2020

Daily News

Arguing for DNA Methylation Changes to be a Contributing Cause of Aging

by Consultant

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Contributing mechanisms of aging form an interconnected network of cause and consequence. For most such mechanisms there is considerable debate over relative importance to the manifestations of aging, as well...

Aug 11 2020

Daily News

IGF-1R Inhibition Reduces Neuroinflammation in an Alzheimer’s Mouse Model

by Consultant

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Chronic inflammation in brain tissue is an important component of the progression of neurodegenerative conditions such as Alzheimer’s disease. It is important enough that some researchers propose inflammation resulting from...

Aug 08 2020

Daily News

Too Much Mitochondrial Fission in the Aging Germline Stem Cells of Flies

by Consultant

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Mitochondria are bacteria-like organelles responsible for producing chemical energy store molecules to power cellular processes. Hundreds of them exist in every cell, constantly undergoing fusion and fission, swapping component parts...

Aug 08 2020

Daily News

Accelerated Osteoporosis in Mitochondrial Mutator Mice

by Consultant

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Mitochondria are the power plants of the cell, the evolved descendants of ancient symbiotic bacteria. They generate the chemical energy store molecules needed to power cellular processes. The herd of...