Category: Medicine, Biotech, Research

Oct 13 2020

Medicine, Biotech, Research

Towards Harnessing Growth to Create Rejuvenation

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A recent pair of open access papers offer an interesting viewpoint on embryonic development, aging, cancer, and possible approaches to rejuvenation in this era of biotechnology. I’m not sure that...

Oct 10 2020

Medicine, Biotech, Research

Fecal Microbiota Transplantation from Old Mice to Young Mice Impairs Cognitive Function

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The microbiome of the gut changes with age, and this is presently thought to have a meaningful influence over the course of aging. It is perhaps in the same ballpark...

Oct 09 2020

Medicine, Biotech, Research

Lamenting the Incomplete Understanding of Human Immunosenescence

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The immune system is inconveniently complicated. Aging is also inconveniently complicated. The overlap between the two is a particularly dark forest for the research community, with few well-tracked paths. The...

Oct 08 2020

Medicine, Biotech, Research

Delivery of T Cell Progenitor Cells as an Approach to Thymic Regeneration

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The thymus is a small organ in which thymocytes generated in the bone marrow mature to become T cells of the adaptive immune system. Unfortunately, the thymus atrophies with age,...

Oct 07 2020

Medicine, Biotech, Research

Targeting Senescent Cells to Reverse the Aging of the Heart

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Almost a decade has passed since the first compelling demonstration that clearance of senescent cells in mice could produce rejuvenation. This validated decades of prior evidence, largely ignored in the...

Oct 06 2020

Medicine, Biotech, Research

There is No Such Thing as Aging

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Today’s open access commentary is intended to provoke discussion on the topic of how aging is thought about and presented, particularly at the intersection between the scientific community and the...

Oct 03 2020

Medicine, Biotech, Research

Building the Glucosepane Research Toolkit Continues with the Creation of Anti-Glucosepane Antibodies

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Glucosepane is likely the most important form of persistent cross-linking in aging human tissue. There is some remaining uncertainty, but it appears that the vast majority of cross-links in old...

Oct 02 2020

Medicine, Biotech, Research

On the Aging of the Germline and Rejuvenation in Embryos

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It is clearly the case that cells and tissues are in principle capable of rejuvenation. Individuals age, but their offspring are born young. The germline in adults is protected in...

Sep 30 2020

Medicine, Biotech, Research

The Aging of Chimpanzees versus that of Humans

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We humans are unusually long-lived in comparison to our near primate cousins, and also compared to other mammals of similar body mass. We also exhibit menopause, an end to reproductive...

Sep 29 2020

Medicine, Biotech, Research

The Old are Becoming Functionally Younger

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Today’s research materials cover one of a number of studies to suggest that older people are becoming functionally younger over time, comparing the capabilities of age-matched cohorts of old people...