Skincare

Aug 27 2020

Medicine, Biotech, Research

Age-Related Downregulation of Rubicon Causes Excessive Autophagy in Adipocytes, Contributing to Metabolic Dysfunction

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Autophagy is a vital collection of cellular maintenance processes in which proteins and structures are broken down and recycled for their component parts. In short-lived laboratory species, dysfunctional autophagy shortens...

Aug 27 2020

Daily News

A Gene Therapy Approach to Clearing Persistent Herpesviruses

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Approaches that might effectively clear herpesviruses from the body are of considerable interest, as there is good evidence for the burden of persistent infection to have a meaningful impact on...

Aug 27 2020

Daily News

Cartilage Regrowth: Steering Microfracture to Provoke Regeneration of Fully Functional Cartilage

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Microfracture surgery is a poor approach to producing the regrowth of cartilage. It is a procedure that causes minor damage, and that damage in turn provokes a more extensive regeneration...

Aug 26 2020

Investment

A Two Part Interview with Greg Bailey of Juvenescence

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Juvenescence and Life Biosciences are presently the two large business development companies in the growing longevity industry. They act much like venture funds, in that they create or take controlling...

Aug 26 2020

Daily News

IL-6 and TGFβ1 Upregulation with Age Cause Detrimental Changes in Hematopoiesis

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Researchers here show that blocking the age-related upregulation of inflammatory signal molecules IL-6 and TGFβ1 can reverse some of the deterimental changes in the function of hematopoiesis. Hematopoiesis is the...

Aug 26 2020

Daily News

Higher Body Mass Index Correlates with Reduced Cerebral Blood Flow

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Vascular aging is an important contribution to neurodegeneration. The brain is an energy-hungry organ, and reductions in blood flow with age have a negative impact on brain tissue. These reductions...

Aug 25 2020

Medicine, Biotech, Research

Destroying Existing Microglia is Necessary for Replacement Strategies to Work

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Today’s open access research is a demonstration in mice of approaches to replace near all microglia in the central nervous system. Microglia are innate immune cells of the brain, involved...

Aug 25 2020

Daily News

DOK7 Gene Therapy Regrows Neuromuscular Junctions to Improve Aged Muscle Function

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One of the numerous possible contributing causes to sarcopenia, the name given to the characteristic age-related decline in muscle mass and strength, is the dysfunction and loss of neuromuscular junctions....

Aug 25 2020

Daily News

The Prospects for LANDO Upregulation as a Treatment for Alzheimer’s Disease

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Of late, researchers have identified a process known as LC3-associated endocytosis (LANDO) by which cells can ingest and then break down the amyloid-β deposits associated with Alzheimer’s disease. This raises...

Aug 24 2020

Newsletters

Fight Aging! Newsletter, August 24th 2020

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....