Skincare

Aug 26 2020

Daily News

IL-6 and TGFβ1 Upregulation with Age Cause Detrimental Changes in Hematopoiesis

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Researchers here show that blocking the age-related upregulation of inflammatory signal molecules IL-6 and TGFβ1 can reverse some of the deterimental changes in the function of hematopoiesis. Hematopoiesis is the...

Aug 26 2020

Daily News

Higher Body Mass Index Correlates with Reduced Cerebral Blood Flow

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Vascular aging is an important contribution to neurodegeneration. The brain is an energy-hungry organ, and reductions in blood flow with age have a negative impact on brain tissue. These reductions...

Aug 25 2020

Medicine, Biotech, Research

Destroying Existing Microglia is Necessary for Replacement Strategies to Work

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Today’s open access research is a demonstration in mice of approaches to replace near all microglia in the central nervous system. Microglia are innate immune cells of the brain, involved...

Aug 25 2020

Daily News

DOK7 Gene Therapy Regrows Neuromuscular Junctions to Improve Aged Muscle Function

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One of the numerous possible contributing causes to sarcopenia, the name given to the characteristic age-related decline in muscle mass and strength, is the dysfunction and loss of neuromuscular junctions....

Aug 25 2020

Daily News

The Prospects for LANDO Upregulation as a Treatment for Alzheimer’s Disease

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Of late, researchers have identified a process known as LC3-associated endocytosis (LANDO) by which cells can ingest and then break down the amyloid-β deposits associated with Alzheimer’s disease. This raises...

Aug 24 2020

Newsletters

Fight Aging! Newsletter, August 24th 2020

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

Aug 22 2020

Activism, Advocacy and Education

Aging Research Should be Far More of a Priority than is Presently the Case

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For our species, aging is by far the greatest single cause of suffering and death. It is presently inevitable, affects everyone, and produces a drawn out decline of pain and...

Aug 22 2020

Daily News

Adenosine Signaling via the A1 Receptor Reverses Age-Related Decline in Neutrophil Function

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Neutrophils are an important component of the innate immune system, mounting a first response to infectious pathogens. An insufficient neutrophil response leads to a far more serious infection. Researchers here...

Aug 22 2020

Daily News

Adenosine Injected into Arthritic Joints Produces Cartilage Regrowth

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Researchers here provide evidence for injections of adenosine into damaged joint tissue to provoke meaningful degrees of cartilage regrowth in an animal model of degenerative joint disease. Finding ways to...

Aug 21 2020

Medicine, Biotech, Research

The Public Cannot Distinguish Between Scientific versus Unscientific, Likely Good versus Likely Bad Approaches to Longevity

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One of the challenges inherent in patient advocacy for greater human longevity, for more research into aging and rejuvenation, is that journalists and the public at large either cannot or...