Skincare

May 07 2020

Daily News

Rapamycin Slows Age-Related Periodontitis in Mice

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The mTOR inhibitor rapamycin slows the progression of aging in mice. The may largely be a result of upregulated autophagy, as is the case for many other means of slowing...

May 06 2020

Medicine, Biotech, Research

α-synuclein Aggregation Impairs Autophagy in Brain Tissue

by Consultant

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Age-related neurodegeneration is characterized by the aggregation of a small number of proteins, including α-synuclein, that can become altered in a manner that encourages other molecules of the same protein...

May 06 2020

Daily News

Hydrogen Treatment Modestly Dampens Oxidative Stress in Nematodes

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Hydrogen can scavenge free radical molecules, and thus act as a form of antioxidant. Researchers here demonstrate that in action in nematode worms. Excessive levels of free radicals such as...

May 06 2020

Daily News

Reducing Neuroinflammation Slows Onset of Neurodegeneration in Animal Models

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Alzheimer’s disease is strongly driven by chronic inflammation in brain tissue. Studies in which senescent, inflammatory microglia are removed from the brain strongly suggests this to be the case in...

May 05 2020

Medicine, Biotech, Research

What is the Degree of Synergy Between Different Longevity-Associated Mechanisms?

by Consultant

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The degree to which interventions targeting different mechanisms associated with longevity might stack or synergize to produce greater gains is a woefully understudied topic. Study of synergies between treatment approaches...

May 05 2020

Daily News

An Example of a Small Molecule Approach to Telomere Lengthening

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Research groups are eyeing telomere lengthening as a way to improve stem cell function. Telomeres are the caps of repeated DNA sequences at the ends of chromosomes. A little of...

May 05 2020

Daily News

The Ordering of Cholesterol Accumulation and Inflammatory Response in Foam Cell Formation

by Consultant

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The development of atherosclerotic lesions involves the dysfunction of macrophage cells. They are normally responsible for removing lipids from lesions and handing it off to HDL particles to be returned...

May 04 2020

Uncategorized

Gene defects linked to eczema, wheeze and nasal disease among babies

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A link has been discovered between a common gene defect and eczema, nasal blockage and wheeze among babies as young as six months, according to a new study. The research raises new questions about how soon in life these defects...

May 04 2020

Newsletters

Fight Aging! Newsletter, May 4th 2020

by Consultant

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

May 02 2020

Medicine, Biotech, Research

Turning Navitoclax into a PROTAC Senolytic with a Better Safety Profile

by Consultant

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It is interesting to compare today’s open access paper on converting the senolytic drug navitoclax into a PROTAC with recent efforts to improve navitoclax by conjugation with galactose. In both...