Skincare

Oct 09 2020

Medicine, Biotech, Research

Lamenting the Incomplete Understanding of Human Immunosenescence

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The immune system is inconveniently complicated. Aging is also inconveniently complicated. The overlap between the two is a particularly dark forest for the research community, with few well-tracked paths. The...

Oct 09 2020

Daily News

Klotho in Aging and the Failing Kidney

by Consultant

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Klotho is one of the few longevity-associated genes with robustly demonstrated effects in both directions: reduce its expression and life span is reduced, increase its expression and life span is...

Oct 09 2020

Daily News

An Example of the Beneficial Role of Senescence in Injury

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Researchers here provide an interesting demonstration of the beneficial role of transient cellular senescence in injury. Applying senolytics to selectively destroy senescent cells immediately following traumatic injury greatly worsens the...

Oct 08 2020

Medicine, Biotech, Research

Delivery of T Cell Progenitor Cells as an Approach to Thymic Regeneration

by Consultant

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The thymus is a small organ in which thymocytes generated in the bone marrow mature to become T cells of the adaptive immune system. Unfortunately, the thymus atrophies with age,...

Oct 08 2020

Daily News

Markers of Chronic Inflammation Correlate with Age-Related Loss of Muscle Mass and Strength

by Consultant

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Chronic inflammation is a sizable component of aging. The immune system becomes inappropriately overactive, disrupting its normal participation in tissue maintenance, and producing alterations in the signaling environment that change...

Oct 08 2020

Daily News

Lef1 Enables Skin Regeneration Without Scarring in Mice

by Consultant

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To achieve regeneration without scarring is an important goal in the medical research community. Some species are capable of proficient regeneration of even whole limbs or internal organs, but mammalian...

Oct 07 2020

Medicine, Biotech, Research

Targeting Senescent Cells to Reverse the Aging of the Heart

by Consultant

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Almost a decade has passed since the first compelling demonstration that clearance of senescent cells in mice could produce rejuvenation. This validated decades of prior evidence, largely ignored in the...

Oct 07 2020

Daily News

Dopaminergenic Neurons Transplanted into Mouse Brains Integrate Into Neural Circuits and Improve Parkinson’s Symptoms

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Researchers here demonstrate that human dopaminergenic neurons, the class of cell lost in Parkinson’s disease, can integrate into neural circuits and improve motor function when transplanted into mice. The challenge...

Oct 07 2020

Daily News

The More Time Spent with High Blood Cholesterol, the Greater the Lifetime Risk of Heart Disease

by Consultant

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Researchers here suggest that the processes of atherosclerosis, leading to the buildup of fatty deposits that narrow and weaken blood vessels, are cumulative over time. One of the risk factors...

Oct 06 2020

Medicine, Biotech, Research

There is No Such Thing as Aging

by Consultant

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Today’s open access commentary is intended to provoke discussion on the topic of how aging is thought about and presented, particularly at the intersection between the scientific community and the...