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Oct 30 2020
Daily News

Proteomic Analysis of Blood Samples Points to the Importance of Inflammation in Aging

by Consultant
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Chronic inflammation is a feature of aging, the constant inappropriate overactivation of the immune system. Many of the mechanisms that contribute to this unfortunate state are catalogued and understood to...
Oct 29 2020
Medicine, Biotech, Research

Another New Senolytic Prodrug is Demonstrated to Reverse Frailty and Cognitive Function in Old Mice

by Consultant
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Today’s open access paper reports on the use of a prodrug senolytic strategy to reverse aspects of aging in mice via the selective destruction of senescent cells. A prodrug is...
Oct 29 2020
Daily News

Resting Metabolic Rate in Aging and Age-Related Disease

by Consultant
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Resting metabolic rate declines with age, a situation that has evolved for perhaps much the same reasons as loss of stem cell function, in that it is one part of...
Oct 29 2020
Daily News

Towards a More Sensitive Blood Test for the Earlier Stages of Alzheimer’s Disease

by Consultant
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The onset of Alzheimer’s disease is preceded by years of slowly growing levels of amyloid-β aggregates in the brain. There is an equilibrium between amyloid-β in the brain and amyloid-β...
Oct 28 2020
Uncategorized

Langerhans cells are up to the job, they just need a chance

by Consultant
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Researchers found that Langerhans cells (LCs) play a crucial role in mucocutaneous acute guest-versus-host disease (aGVHD). Their experiments in mice showed that when the LCs of a recipient were depleted,...
Oct 28 2020
Medicine, Biotech, Research

Wnt Signaling in Neurogenesis and the Aging of the Brain

by Consultant
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The Wnt signaling pathway is found somewhere in the midst of the exceedingly complicated network of processes that regulate regeneration and stem cell function. This small slice of cellular biochemistry...
Oct 28 2020
Daily News

Cellular Senescence as an Important Cause of Non-Healing Wounds in Diabetes

by Consultant
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One of the many unpleasant complications produced by type 1 and type 2 diabetes is a much reduced ability to heal wounds, leading to ulcers and non-healing injuries. Following the...
Oct 28 2020
Daily News

Magnetic Fields Used to Engineer Better Cartilage with a More Natural Variation in Cell Density

by Consultant
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Researchers here demonstrate the use of magnetic fields and fluids to produce a more natural cell density gradient in engineered cartilage tissue. The result is bioartificial cartilage with better structural...
Oct 27 2020
Medicine, Biotech, Research

Research into the Mechanisms of Aging is Very Poorly Funded in Comparison to its Importance to Health

by Consultant
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Research into aging is sparsely funded in comparison to research into the biochemistry and treatment of any specific common age-related disease, such as atherosclerosis or Alzheimer’s disease. Yet these conditions...
Oct 27 2020
Daily News

Targeting Aging is the Way to Treat Diseases of Aging

by Consultant
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Near all work to date on the treatment of age-related disease has failed to consider or target underlying mechanisms of aging, the molecular damage that accumulates to cause pathology. It...

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