Skincare

Aug 11 2020

Daily News

IGF-1R Inhibition Reduces Neuroinflammation in an Alzheimer’s Mouse Model

by Consultant

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Chronic inflammation in brain tissue is an important component of the progression of neurodegenerative conditions such as Alzheimer’s disease. It is important enough that some researchers propose inflammation resulting from...

Aug 11 2020

Daily News

Arguing for DNA Methylation Changes to be a Contributing Cause of Aging

by Consultant

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Contributing mechanisms of aging form an interconnected network of cause and consequence. For most such mechanisms there is considerable debate over relative importance to the manifestations of aging, as well...

Aug 10 2020

Newsletters

Fight Aging! Newsletter, August 10th 2020

by Consultant

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

Aug 08 2020

Medicine, Biotech, Research

Short Term Cdc42 Inhibition In Middle Aged Mice Extends Median and Maximum Life Span

by Consultant

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An interesting study of mouse life span extension via a novel methodology was recently published. The researchers developed a small molecule approach to inhibition of Cdc42, a protein with numerous...

Aug 08 2020

Daily News

Accelerated Osteoporosis in Mitochondrial Mutator Mice

by Consultant

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Mitochondria are the power plants of the cell, the evolved descendants of ancient symbiotic bacteria. They generate the chemical energy store molecules needed to power cellular processes. The herd of...

Aug 08 2020

Daily News

Too Much Mitochondrial Fission in the Aging Germline Stem Cells of Flies

by Consultant

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Mitochondria are bacteria-like organelles responsible for producing chemical energy store molecules to power cellular processes. Hundreds of them exist in every cell, constantly undergoing fusion and fission, swapping component parts...

Aug 07 2020

Medicine, Biotech, Research

Delivery of BDNF Reverses Inflammatory Microglial Activation in Old Mice

by Consultant

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Brain-derived neurotrophic factor (BDNF) shows up in many aspects of the interaction between health practices, mechanisms of aging, and mechanisms of neurodegeneration. Most research is focused on the effects of...

Aug 07 2020

Daily News

An Update on Single Issue Political Advocacy for Longevity in Europe

by Consultant

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In most European countries, electoral rules are such that it is possible to conduct effective advocacy for a cause via a single issue political party. Successful examples include the Green...

Aug 07 2020

Daily News

The Reasons to Study Aging

by Consultant

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I point out this open access paper not for the content, but for the preamble, in which the author offers a view on why the research community should study aging....

Aug 06 2020

Investment

Biotech Startup SENISCA Develops a RNA Splicing Approach to the Treatment of Aging

by Consultant

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In recent years, increasing attention has been given to RNA splicing as a mechanism of interest in aging. RNA splicing is the process of combining intron and exon regions derived...