Skincare

Aug 13 2020

Daily News

A Fisetin Variant, CMS121, Slows Disease Progress in an Alzheimer’s Mouse Model

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The research materials here are of interest because fisetin has been shown to be a senolytic compound in mice, capable of selectively destroying harmful senescent cells. Other senolytics have reversed...

Aug 12 2020

Medicine, Biotech, Research

Telomerase Gene Therapy May Treat Fibrosis via a Reduced Burden of Cellular Senescence

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A number of research groups are quite enthusiastic about the prospects for telomerase gene therapy as a treatment for aging and numerous age-related diseases. This is based on more than...

Aug 12 2020

Daily News

Overexpression of VRK-1 Extends Life Span in Nematode Worms

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A great many approaches exist to slow aging in short-lived laboratory species such as nematodes, flies, and mice. The example here is an illustrative example, similar to dozens of other...

Aug 12 2020

Daily News

The Gut Microbiome Changes Shortly Before Death in Centenarians

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Extremely old people have such high mortality rates that studies such as this one here become practical, answering the question of how the gut microbiome changes in the final decline...

Aug 11 2020

2020, Anti-Aging, Best Sunscreens, Clear & Brilliant Laser, Melasma

When should you ask for a refund?

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This is an important question.  But maybe even more important is …how do you ask for a refund.  This is a tough skill to learn even for some seasoned negotiators...

Aug 11 2020

Medicine, Biotech, Research

30% to 40% of Dementia Might be Avoided via Lifestyle Choices

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Today’s open access research materials present a statistical exercise that uses broad epidemiological data to determine the impact of individual lifestyle choices and environmental factors to the incidence of dementia....

Aug 11 2020

Daily News

IGF-1R Inhibition Reduces Neuroinflammation in an Alzheimer’s Mouse Model

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Chronic inflammation in brain tissue is an important component of the progression of neurodegenerative conditions such as Alzheimer’s disease. It is important enough that some researchers propose inflammation resulting from...

Aug 11 2020

Daily News

Arguing for DNA Methylation Changes to be a Contributing Cause of Aging

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Contributing mechanisms of aging form an interconnected network of cause and consequence. For most such mechanisms there is considerable debate over relative importance to the manifestations of aging, as well...

Aug 10 2020

Newsletters

Fight Aging! Newsletter, August 10th 2020

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine....

Aug 08 2020

Medicine, Biotech, Research

Short Term Cdc42 Inhibition In Middle Aged Mice Extends Median and Maximum Life Span

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An interesting study of mouse life span extension via a novel methodology was recently published. The researchers developed a small molecule approach to inhibition of Cdc42, a protein with numerous...